Fig. 4

Structure-based sequence alignment of VP8*s in Chimera. The residues known to bind glycans are indicated with colored shade. The glycan binding amino acids that are conserved or non-conserved in the prevalent strains (P[6], P[4], P[8], and P[19]) are denoted with black and blue shades, respectively. The precursor glycan binding sites in P[11] RVs are labeled with light red shade. The A-type HBGA binding site in P[14] RV, and the sialic acid binding residues in P[3] and P[7] RVs are denoted with green shade. The PDB IDs for each structure are shown by the sequences