Fig. 6 | Nature Communications

Fig. 6

From: Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics

Fig. 6

Drug sensitivity profiling of 24 compounds against nine EAC organoids. Organoid cultures are clustered based on their drug sensitivity as measured by 1-AUC values across the drug panel. The drug names are provided at the bottom of the panel and the mutational signature subtype also indicated. Asterisks (*) identify drugs that elicited an IC50 below 1 µM while the histogram indicates the number of drugs for each organoid culture eliciting an IC50 below 1 or 0.1 μM

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