Fig. 2

Evolutionary trees of PCRCs. Ten evolutionary trees were constructed from the multiregion WES data using the Treeomics algorithm. Trunks, internal branches (int-Br), and external branches (ext-Br) generally correspond to ubiquitous, shared, and private mutations, respectively, while leaves correspond to samples. The colors of the leaves are the same as the sample labels in Fig. 1. Lengths of the trunk and branches represent the number of mutations, and scales for ten mutations are shown near the roots of the evolutionary trees. Driver genes with possible functional mutations are mapped along the evolutionary trees. The photo of each tumor is provided with positions from which each sample was obtained. Red scale bars for one centimeter attempted with each photo