Fig. 10
From: Non plasmonic semiconductor quantum SERS probe as a pathway for in vitro cancer detection
In vitro SERS detection up to a single-cell level. a Simultaneous signal enhancement from multiple biomolecules was due to the cellular uptake and internalization of the quantum probes. Scale bar 2 µm for (i) and 500 nm for (ii–v). b SERS spectra from single cells reveal that the entrapment of the quantum probes in the lysosomes does not have any adverse effect on signal enhancement. c Single-cell Raman mapping indicates ability of the quantum probe up to single-cell-level detection. Scale bar = 20 µm. d Different size of the probe plays an important role in the SERS showing ability to design variety of probes based on cellular affinity. The “x” axis of the spectra display Raman Shift (cm−1) and “y” axis displays arbitrary units
