Fig. 3 | Nature Communications

Fig. 3

From: Structural basis for endotoxin neutralisation and anti-inflammatory activity of thrombin-derived C-terminal peptides

Fig. 3

tr-NOESY spectrum of HVF18 in LPS micelles. Two-dimensional 1H–1H tr-NOESY spectrum of HVF18 (0.5 mM) in the presence of LPS (20 μM) (a) showing NOE connectivities involving W8 indole proton with the upfield shifted aliphatic proton resonances. b Finger print region showing sequential and medium range NOE connectivities between backbone alpha and amide proton (CαH/HN) resonances, (c) section showing NOE connectivities among backbone amide (HN/HN) resonances and (d) section showing NOE connectivities between the aromatic ring protons of F3, F16, and W8 with the upfield shifted aliphatic proton resonances. tr-NOESY spectrum of HVF18 in LPS micelles was obtained in aqueous solution (pH 4.5) at 298 K in a Bruker DRX 600 MHz NMR instrument

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