Fig. 1
From: Identification of recurrent USP48 and BRAF mutations in Cushing’s disease
Whole-exome sequencing and targeted sequencing in corticotroph adenomas. a Percentage of non-silent somatic SNVs identified by whole-exome sequencing in 22 subjects with corticotroph adenomas carrying wild-type USP8. b The number and type of somatic mutations identified by whole-exome sequencing (top). The mutational status of the indicated genes in each patient is shown at the bottom. c Mutation frequency of the indicated genes in corticotroph adenomas with wild-type or mutated USP8 by targeted sequencing. Each column represents a single case. n: number of subjects. Patients with the indicated mutations are marked in blue (b, c)
