Fig. 5
From: Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis
Hepatic ablation of Blnc1 stimulates thermogenesis and energy expenditure. a, b VO2 and energy expenditure (a), food intake and total activity (b) in ctrl (filled, n = 8) and LKO (open, n = 8) mice fed HFD for 15 weeks. Data in (a) and (b) represent mean ± SEM. *p < 0.05; ctrl vs. LKO, two-tailed unpaired Student’s t-test. c H&E staining of BAT section from HFD-fed mice. Scale bar = 100 μm. d qPCR analysis of brown fat gene expression in HFD-fed ctrl (filled, n = 9) and LKO (open, n = 9) mice. Data represent mean ± SEM. *p < 0.05, **p < 0.01; ctrl vs. LKO, two-tailed unpaired Student’s t-test
