Fig. 5
From: Size control in mammalian cells involves modulation of both growth rate and cell cycle duration
S-G2 duration is negatively correlated with volume at G1/S in HeLa but not HT29 cell. a Duration of S-G2 phase, ΔtS−G2 vs. the logarithm of volume at G1/S transition (VG1/S) for HT29-hgem (N = 4). b Added volume in S-G2 phase, ΔVS−G2 vs. volume at G1/S transition (VG1/S) for HT29-hgem (N = 4). c Duration of S-G2 phase, ΔtS−G2 vs. the logarithm of volume at G1/S transition (VG−S) for HeLa-hgem (N = 2). d Added volume in S-G2 phase, ΔVS−G2 vs. volume at G1/S transition (VG1/S) for HeLa-hgem (N = 2). e, f Added volume in S-G2, ΔVS−G2 vs. added volume in G1 (VG1) for HT29-hgem (N = 4) (e) and HeLa-hgem (N = 2) (f). Dashed black line represents the slope expected in the case of a mechanistic adder where: ΔVS−G2=〈ΔVTOT〉−ΔVG1 (slope of −1). g, h Added volume in the whole cell cycle ΔVTOT vs. volume at birth (Vbirth) for HT29-hgem (N = 4) (g) and HeLa-hgem (N = 2) (f). For all the plots in this figure, individual cell measures (dots) and median bins (squares) ± s.d. (bars) are shown. Solid line is a linear regression on the median bins weighted by the number of observations in each bin. See also Supplementary Figure 5
