Fig. 7

CD4 depletion in RMs reduces CD127 surface expression on MLN ILCs. a Representative dot plots of IL-18Rα expression on ST2 and c-Kit-expressing hematopoietic cells in the MLN. b MLN ILCs were defined by CD127 surface expression and IL-18Rα MFI was assessed on MLN ILCs from healthy uninfected (N = 8) and chronic SIV⁺ RMs (N = 7). c ILCs were defined by IL-18Rα surface expression and CD127 MFI were assessed on MLN ILCs from SIV⁻ healthy control (N = 8) and DSS⁺ αCD4⁺ RMs (N = 5). d Summary data of CD127 surface expression on IL-18Rα-expressing ILCs in the SIV-uninfected and chronic SIV⁺ MLN (N = 7). Statistical significance in panels b–d were calculated using the Mann-Whitney test. ns = P > 0.05, * = P ≤ 0.05, ** = P ≤ 0.01, *** = P ≤ 0.001, and **** = P ≤ 0.0001