Fig. 4
From: Hapten-mediated recruitment of polyclonal antibodies to tumors engenders antitumor immunity

FcR expression dependence of VEGF–DNP-mediated tumor inhibition in DNP immune mice. Wild type (a) and FcR-deficient (b) C57BL/6 mice were immunized against DNP (DNP-KLH) or mock immunized (KLH), challenged subcutaneously with MC38 tumors and 4–5 days later when tumors became palpable mice were treated with VEGF–DNP conjugate and tumor growth was measured. Statistical analysis (a), VEGF–DNP in DNP-KLH versus KLH vaccinated mice, **p = 0.0025, student’s t-test (7 mice per group) (n = 1); ns not significant (p > 0.05). Data are represented as mean ± SEM