Fig. 4

Total chemical synthesis of CSP-1. a The CSP-1 sequence where the two-ligation sites are underlined. b Synthesis of CSP-1, analytical HPLC and mass traces for purified CSP-1 with the observed mass 12589 ± 1.1 Da, calcd 12590 Da (average isotopes) and CD spectrum. R1: 3-Mercaptopropionate, N-MeNbz: N-acyl-N′-methylacylurea