Table 2 Kaplan−Meier survival analysis of OSCC patients according to the levels of protein expression obtained by IHC analysis
From: Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
Parameter | Disease-free survival in 5 years % (n) | HR; CI (P value) | Specific survival in 5 years % (n) | HR; CI (P value) |
|---|---|---|---|---|
CSTB | ||||
Lower expression in ITF | 45% (25) | 54% (26) | ||
Equal expression | 76% (15) | 81% (11) | ||
Higher expression in ITF | 86% (44) | 0.21; 0.07−0.60 (0.001) | 90% (40) | 0.28; 0.10−0.79 (0.01) |
NDRG1 | ||||
Lower expression in ITF | 44% (43) | — | — | |
Equal expression | 83% (35) | — | — | |
Higher expression in ITF | 100% (11) | 0.31; 0.12−0.79 (0.01) | — | — |
PGK1 | ||||
Lower expression in ITF | 82% (24) | 82% (25) | ||
Equal expression | 50% (44) | 61% (42) | ||
Higher expression in ITF | 50% (48) | 3.22; 1.45−7.15 (0.02) | 52% (42) | 3.96; 1.82−8.64 (0.005) |
ITGAV | ||||
Lower expression in ITF | 100% (10) | 100% (08) | ||
Equal expression | 90% (52) | 92% (50) | ||
Higher expression in ITF | 65% (17) | 4.02; 0.77−20.76 (0.02) | 72% (16) | 4.99; 0.90−27.68 (0.01) |
