Fig. 7
From: Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes
Molecular regulation of the subcapsular proliferative foci. a Enumeration of population 1, 2 and 3 in the secondary response following inducible deletion of MHCII. Data is representative of three experiments with n = 6 each group. Comparison between groups utilised one-tailed unpaired Student’s t-test. b Enumeration of population 1, 2 and 3 in the secondary response following ibrutinib treatment after reactivation of MBCs. Data are representative of 2 experiments with n = 5 each group. Comparison between groups utilised one-tailed unpaired Student’s t-test. Box plots show centre line as median, box limits as upper and lower quartiles, whiskers as minimum to maximum values. c Representative immunohistochemical analysis of draining cervical lymph node from a patient with head and neck cancer showing CD169 (brown) and CD138 (red) expression. Hematoxylin nuclear counterstain (blue). Scale bar = 100 μm
