Fig. 4 | Nature Communications

Fig. 4

From: Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area

Fig. 4

Corticostriatal topographic precision across cortical areas and cell types. a, b Pairwise correlation between ipsilateral corticostriatal projections from IT-type (a, b) and PT-type (c, d) neurons was plotted against injection site offset in mm. Scale, 1 mm. a, c Dorsal view of injection sites in CCF coordinates. Midline and bregma indicated at right. Scale bars, 1 mm. All primary sensory (S1) injections are shown in blue and primary motor (M1) injections are shown in pink. Circles indicate injection site with injection number labeled. Double headed arrow indicates injection site offset distance for one pair of injections. b, d, f Correlation versus injection site offset for S1 and M1 injections. N = 351, IT-type vs. IT-type in S1; N = 435, IT-type vs. IT-type in M1; N = 312, PT-type vs. PT-type in S1; N = 300, PT-type vs. PT-type in M1; N = 702, IT-type vs. PT-type in S1; N = 750, IT-type vs. PT-type in M1). Solid line represents linear fit, with confidence interval plotted as dashed lines. Typographic marks indicate y-intercept across panels for comparison. e Mean number of overlapping voxels used to calculate correlations for IT–IT (b), PT–PT (d) and IT-PT (f) comparisons. f Correlation versus injection site offset for comparisons across IT-type and PT-type injections in S1 and M1. Here, each S1 IT-type injection is compared to each S1 PT-type injection but not to other IT-type injections

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