Table 2 Accuracy of rVAR2-based recovery of PDAC cells spiked into 5 mL of blood from healthy donors

From: The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner

PDAC cells added

Average recovery (%)

S.E.M. (n=5)

3a

60.0

12.5

6a

76.7

8.5

10

86.0

10.8

20

91.0

7.0

50

88.0

5.3

100

88.6

1.2

200

91.9

1.3

500

88.8

4.9

  1. aThe accuracy of recovery of three and six cells were done using GFP-expressing PDAC cells spiked into 5 mL of blood from healthy donors (n = 5). The number of cells used for spiking was visually confirmed before and after aspiration. Spiked samples were enriched for cancer cells using rVAR2-coated beads in combination with the IsoFlux™ and enumerated based on the detection of the GFP signal.
  2. S.E.M. standard error of the mean