Fig. 2
From: Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution
Bioinformatic analyses of the antimycin PKS modules. a Alignment of the PKS modules, AntD, SmlC, and NatC. We annotated SmlC1301–1371 as an ACP domain (region 1), SmlC1372–1392 as an interdomain linker, SmlC1393–1647 as a TE domain (region 2), and NatC1391–1411 as a docking domain. b A homology model of ACPNatC (1320–1411), based on the reported crystal structure of the surfactin synthase ACP subunit (PBD: 2VSQ) as the template. c A homology model of the ACPNatC-TESmlC domains, the NRPS module from Acinetobacter baumannii (NCBI PBD ID 4ZXH_A, https://www.ncbi.nlm.nih.gov/protein/4ZXH_A) was used as the template
