Fig. 3
From: Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution
Ring contraction of neoantimycin A. a The reconstructed module structure for ring contraction. b HPLC analyses of the metabolites from transformants harboring (i) pKU518nant and (ii) pKU518nantΔnatD::smlCTE. The chromatogram represents the UV absorbance at 320 nm. * and ** indicate unidentified analogs with m/z values that were 14 and 28 less than 3b, respectively. c Engineering scheme and structure of 4
