Fig. 9 | Nature Communications

Fig. 9

From: Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis

Fig. 9

Oral feeding butyrate protects colitis development induced by DSS. B6 mice were administered 1.7% DSS in drinking water for 7 days, followed by 3 days of water. One group (n = 4–5) of mice were fed with butyrate (C4, 200 mM) in drinking water from day 0 when DSS was given. a Representative images of histopathology in cecum. Scale bar, 100 μm. b Histopathological scoring. **p < 0.01 Mann–Whitney U-test. c LP CD4+ T-cell IL-10 and IFNγ production was determined by flow cytometry. d Bar charts of the percentage of IL-10-expressing CD4+ T-cells. n = 4–5 per group per experiment. Data are one representative of 2 independent experiments; *p < 0.05 Student’s t-test

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