Fig. 6
From: Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses
Structures of cargo-free importin α1 and α3 confirm ARMs 7 and 8 positioning. a Importin α1 cargo-free structure and structural superposition with importin α1:HeV W complex (reference molecule, coloured yellow) and associated r.m.s.d plot. The positioning of the α-helices in ARM repeats 7 and 8 are static across all structures. The importin α1 is coloured by r.m.s.d rendering where blue < 2.5 Å variance, and red for variances above 2.5 Å. b Importin α3 cargo-free structure, together with the associated structural superposition with importin α3:HeV W complex, and r.m.s.d plot. Importin α structures were aligned in UCSF Chimera using MatchEnsemble, and r.m.s.d. plots were generated using MatchAlign, and MatchAssess functions. Colouring as per a, but with importin α3:HeV W in orange
