Fig. 2
From: Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay
Substrate scope. a Scope of alkenes. b Scope of acyl chlorides. c Scope of fluoroalkyl iodides. Reaction conditions: NiCl2•glyme (10 mol%), dtbbpy (20 mol%), alkene (1.0 equiv.), RfI (1.0 equiv.), acyl chloride (1.5 equiv.), Mn (3.0 equiv.), CH3CN [0.1 M], 25 oC, 20 h, see Supplementary Methods. All cited yields are isolated yields. Ar = 4-tert-butylphenyl, R = C6H13CO2. a Performed with 20 mol% NiCl2•glyme. b Reaction concentration is 0.05M CH3CN. cPerformed in CH3CN/DME (4:1) [0.1 M]
