Table 1 Impact of potential substrates and effectors on ATP transport by SLC35B1
From: AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum
Effector | SLC35B1 | SLC35B1/1isoform 2 | ||
|---|---|---|---|---|
Transport (%) | ± SEM (%) | Transport (%) | ± SEM (%) | |
ATP | 37.1 | 4.5 | 31.2 | 3.0 |
ADP | 48.6 | 3.1 | 43.5 | 3.7 |
AMP | 85.1 | 7.4 | 88.0 | 4.3 |
UTP | 114.0 | 12.6 | 106.4 | 12.9 |
GTP | 124.2 | 16.5 | 100.1 | 11.9 |
CTP | 122.6 | 10.2 | 109.2 | 7.7 |
UDP glucose | 129.5 | 13.5 | 105.9 | 8.4 |
UDP galactose | 107.3 | 5.6 | 93.9 | 1.5 |
UMP | 105.4 | 14.6 | 98.1 | 3.9 |
UDP | 126.8 | 19.5 | 92.7 | 2.9 |
UDP-Nac-Glc-AmN | 120.5 | 13.9 | 106.5 | 12.3 |
GDP mannose | 110.4 | 3.7 | 99.5 | 7.9 |
Mg2+ 500 µM | 113.4 | 9.6 | 106.5 | 5.2 |
Ca2+ 10 µM | 105.5 | 7.6 | 106.7 | 12.5 |
Ca2+ 50 µM | 119.8 | 19.0 | 109.6 | 7.0 |
EDTA 200 µM | 146.8 | 10.8 | 114.0 | 10.8 |
EGTA 20 µM | 114.6 | 4.9 | 103.6 | 6.2 |
EGTA 200 µM | 120.8 | 9.2 | 105.3 | 8.6 |
