Fig. 3 | Nature Communications

Fig. 3

From: Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells

Fig. 3

Gene expression profiling of cell cycle-restricted pre-leukemic stem cells (pre-LSCs). Gene set enrichment analysis (GSEA) of a cell cycle, p53-mediated response and apoptosis genes, b DNA replication genes, c homologous recombination genes and d cell-cycle genes downregulated in quiescent GFPhi HSCs from ref.29. GFP green fluorescent protein, FDR false discovery rate, NES normalized enrichment score in GFPhi as compared to GFPlo population

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