Fig. 3
GEM-predicted catabolic capabilities across 53 non-host-specific serovars. a Eight serovars of S. enterica subsp. enterica can be classified based on their ability to catabolize six nutrients: d-tagatose, Xanthosine 5′-phosphate, Myo-inositol, d-glyceraldehyde (anaerobically) and Aminoethylphosphonate (AEP). For purposes of clarity, serovars were included in this classification when there were more than 5 strains in the dataset that represented it. The ability to catabolize a given nutrient always leads to the right while the inability to catabolize the listed nutrient leads to the left. Note that glycolate utilization was removed from the features used to build the decision tree (see Supplementary File 1). b The catabolic capabilities of the 410 GEMs across 323 nutrient sources in 532 media conditions were computed. Here the catabolic capabilities for 53 generalists across 19 simulated nutrient environments are shown (see Supplementary Fig. 4 for a detailed list). Each strain is randomly chosen as a representative of a serovar. Growth of a particular strain in a particular medium condition (represented by a dark blue color) demonstrates a positive GEM predicted nutrient utilization capability. The full dataset for catabolic capability predictions across all strains is found in Supplementary Data 4. Serovar names are listed along with an arrow pointing to the row it corresponds to in the cluster map
