Fig. 5
From: Converting organosulfur compounds to inorganic polysulfides against resistant bacterial infections
Infected-wound healing using nFeS regimen. a Morphology of P. aeruginosa before (control) and after Cys-nFeS treatment. The red triangles indicate flagella. Scale bars: 1 µm. b Photographs of P. aeruginosa infected wounds treated with buffer (control), Cys-nFeS, H2O2, and Cys-nFeS + H2O2 at different times (five mice in each group). c Histologic analyses of the corresponding treated wounds in (b) at day 6. Scale bars: 500 µm. d Influence of Cys-nFeS on the viability of fibroblast cells. e Influence of the supernatant from Cys-nFeS on the viability of fibroblast cells. f Stimulation of fibroblast cell proliferation by Fe3O4 nanoparticles. Data are shown as the mean ± s.d. Statistical significance was assessed using an unpaired Student’s two-sided t-test compared to the control group. **p < 0.01, ***p < 0.001 and ****p < 0.0001. Mean values and error bars were defined as mean and s.d., respectively. All experiments were performed in triplicate, representative images are shown
