Fig. 4
Model-based predicted survival rate (plain lines) and Kaplan–Meier survival curves and 95% confidence interval (shaded areas) for each dosing regimen group. Top left: cynomolgus experiment control pooled from the 4 experiments (N = 28), top right: favipiravir 100 mg kg−1 BID (N = 6), bottom left: favipiravir 150 mg kg−1 BID (N = 5), bottom right: favipiravir 180 mg kg−1 BID (N = 5). In each panel, model-based predicted survival rate was calculated by simulating 1000 individuals for each dosing regimen and taking the medians of the predicted individual survival functions at each time
