Fig. 5
From: Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis

Alternate homodimerization mode of LkcE relative to hMAO B and 6HDNO. a Homodimeric structure of LkcE. b Homodimerization mode of 6HDNO. The dimer is superimposed on one monomer of LkcE (in blue in a), in the same orientation. c Homodimerization mode of hMAO B. Again, the dimer has been superimposed on a monomer of LkcE. d Interaction surface between the two monomers in LkcE (yellow), hMAO B (red), and 6HDNO (green), relative to a monomer of LkcE. This analysis clearly shows that the mode of homodimerization of LkcE, as well as its overall quarternary organization, differ from these two homologs