Fig. 2
From: Astrocytes integrate and drive action potential firing in inhibitory subnetworks
Depolarizing astrocytes enhances induction of barrage firing. a Effect of bath application of 30 µM BaCl2 on the membrane potential of an NPY interneuron (green) and astrocyte (red) during an example double recording. b Change in membrane potential of NPY interneurons and astrocytes in response to bath application of BaCl2 for all recordings (n = 6 double recordings from 3 mice; paired t test, **p = 0.01). c Example recording showing the effect of BaCl2 on astrocyte depolarization, which results in earlier barrage firing generation. Scale bars, 35 mV, 1 s. d BaCl2 application resulted in a decrease in the number of action potentials required for barrage firing induction (n = 6; paired t test, **p = 0.002). e BaCl2 application did not affect the duration of barrage firing (n = 6). Data are represented as mean ± SEM
