Fig. 5
From: Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo
PK of GRFT in vaginal washes of DMPA-treated mice. Vaginal washes were collected from 5–6 mice per time point at 0.5, 1, 2, 4, 6, 8, 24, 48, and 72 h after FDI insertion. Separate mice were measured at each time point. The levels of GRFT equivalent to 100-fold above the anti-HIV EC90 and 100-fold above the anti-HSV-2 EC90 are both shown (blue dotted lines) as is the LLOQ of GRFT (red dotted line) in mouse vaginal washes (5 ng/ml). Each symbol with error bars indicates the mean ± SEM of the mice in that group
