Fig. 8 | Nature Communications

Fig. 8

From: Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery

Fig. 8

Impacts of mutagenised DmtA1 on the final cyclization reaction. a Predicted DmtA1 model generated by utilizing TMRPres2D. b HPLC traces of ΔdmtA1 complemented with different dmtA1 variants (also see Supplementary Fig. 59). The cyclization products 9 and 12 were indicated in red. c Relative formation of DMT G (9) production in ΔdmtA1 complemented with different dmtA1 variants in comparison to complementation with wild-type dmtA1 (WT). Error bars represent ± s.d. of three independent experiments

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