Fig. 4
From: Haplosaurus computes protein haplotypes for use in precision drug design
Frequency of C5 protein haplotypes by population. Haplotypes are included in the plots if their frequency is ≥ 1% in one or more of the populations. The haplotype C5:802V>I,855R>H, which results in loss of activity of eculizumab is highlighted in red. Data for C5 are taken from http://grch37.ensembl.org/Homo_sapiens/Transcript/Haplotypes?t=C5-001
