Table 1 List of human tumors with the reported chromosome breaks around the centromere region
Chromosome involved | Type of tumor | Technique(s) used | Reference |
|---|---|---|---|
18, 8, 7 | Breast cancer | FISH, aCGH | |
1, 18 | Melanoma | FISH | |
18 | Colorectal | FISH | Alsop et al.18 |
18, 8 | Pancreatic | FISH, aCGH | |
Several | Squamous cell carcinoma | FISH, SKY, aCGH | Hermsen et al.28 |
Several | Adenocarcinoma | FISH, SKY, aCGH | Hermsen et al.28 |
Several | Oral squamous cell carcinoma | FISH | Hermsen et al.29 |
Mostly 3, 5 | Head and neck squamous cell carcinoma | FISH, fiber-FISH, aCGH, MLPA | |
1 | Non-Hodgkin’s lymphoma | FISH | Baccon et al.32 |
1 | Multiple myeloma | FISH | Baccon et al.32 |
1 | Ovarian cancer | FISH | Thompson et al.33 |
10, 14, 7, 21 | Cervical squamous cell carcinoma | FISH | Backsch et al.20 |
Mostly 17 | Hematologic malignancies | FISH | Adeyinka et al.21 |
Several | Prostate cancer | G-banding, SKY | Balachandar et al.22 |
17 | Male breast cancer | MLPA, FISH | Lacle et al.23 |
1, 8 | Hepatocellular carcinoma | Whole genome sequencing, aCGH | Fernandez-Banet et al.24 |
1, 7 | Acute myeloid leukemia | FISH | Ganly et al.25 |