Fig. 2 | Nature Communications

Fig. 2

From: Molecular architecture and regulation of BCL10-MALT1 filaments

Fig. 2

Core structure of the BCL10 CARD filament. a, b Top and side view of the BCL10 protein model obtained by interpretation of the BCL10-MALT1 complex cryo-EM density. c Schematic diagram of the BCL10 helical assembly. Each CARD is represented as a hexagon and the three interfaces are indicated accordingly. d, f Detailed view of the three BCL10 interaction surfaces I (d), II (e), and III (f). Interacting residues are shown in stick representation. Sites mutated R42, R36 are highlighted in magenta

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