Table 1 Summary of analyzed samples

From: Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control

 

Control (NC)

Healthy obese (HO)

Steatosis (STEA)

Early NASH (EARLY)

N

4

5

5

5

Male %

25

20

40

40

BMI

26 (22–27)

41 (32–47)

46 (32–62)

51 (40–60)

Age, years

57 (54–62)

36 (29–68)

46 (34–67)

44 (41–58)

Fat content, %

0

0 (0–5)

70 (35–90)

40 (40–50)

Inflammation

0

0 (0–1)

0

1 (1–1)

Fibrosis

0

0

0 (0–1)

0 (0–1)

Ballooning

0

0

0

0 (0–1)

NAS

0

0

3 (1–3)

3 (2–4)

  1. The number of patients in each phenotypic category is provided together with demographic and histologic characteristics. All numeric traits are shown as the median with the range provided in parenthesis. BMI, body mass index; NAS, NAFLD activity score20