Fig. 5
From: Immune-suppression by OsHV-1 viral infection causes fatal bacteraemia in Pacific oysters
The resistant RF21 oysters display an early antiviral response that is delayed in the SF11 susceptible oysters. a The number of genes that were differentially expressed during the ‘natural’ experimental infection was higher in RF21 (green) than in SF11 (blue) oysters before 24 h (early response). This trend was reversed after 24 h and until the end of the infection (late response). Upregulated genes are represented as filled coloured bars and downregulated genes are represented as hatched bars. b Heatmap focusing on the two clusters containing 29 immune-related GO categories that were significantly enriched at 6 and 12 h (FDR < 1%; clusters A and B, Supplementary Fig. 10). c Heatmap of the 220 significantly enriched GO categories (FDR < 1%, biological processes root) clustered according to the Pearson correlation (numbered filled bar). The enrichment intensity was expressed as the ratio between the number of genes that were significantly up- (yellow heat) or downregulated (blue heat) in the category compared with the total number of genes in the category. If the intensity was equal to zero (black heat), then the enrichment was not significant for the corresponding condition. Detailed results (cluster number, GO terms and enrichment values) are presented in Supplementary Data 4
