Fig. 6
From: Direct protein-lipid interactions shape the conformational landscape of secondary transporters

Disruption of conserved charge networks abolishes or decreases lipid-induced conformational shift. ΔHDX of XylE in PE:PG:CL nanodiscs (native-like) minus PC:PG:CL (control) nanodiscs mapped on the PDB structure and the topological representation of XylE for (a) XylE E153Q and (b) XylE E397Q. All measurements were performed in triplicates