Fig. 9 | Nature Communications

Fig. 9

From: Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma

Fig. 9

Phylogenetic study of whole EBV genomes in the newly established NPC models. De novo assembly of EBV whole-genome sequences was performed using WGS data. The assembled sequences were further subjected to phylogenetic analysis comparing with the currently publicly available EBV sequences. The phylogeny tree is drawn to scale, with branch lengths in the same units as those of the evolutionary distances used to infer the phylogenetic tree. The evolutionary distances were computed using the Maximum Composite Likelihood method. Arrows: EBV sequences in the newly established NPC PDXs and cell line, which show significant phylogenetic similarity with EBV sequences previously reported in NPC

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