Fig. 6
From: Network integration of multi-tumour omics data suggests novel targeting strategies
Sensitivity to drugs targeting signature genes. We retrieved drug screening data from the GDSC project and considered the cell lines associated to the tumours in our clusters. The significance was evaluated with Student’s t test (two-sided p-value < 0.05). The continuous horizontal line is the median, the lower and upper boundary represents the 25th and 75th percentiles, respectively. Whiskers extend to data points that lie within 1.5 interquartile ranges of the lower and upper quartiles; and observations that fall outside this range are displayed independently. Blue boxplots: IC50 values for signature genes; green boxplots: IC50 values for all other genes in GDSC targeting the same cell line
