Fig. 2
From: Sexual rejection via a vomeronasal receptor-triggered limbic circuit
ESP22 counteracts ESP1-mediated sexual facilitation and elicits reproductive suppression. a Timeline for female sexual behavior assays. b Raster plots as detailed in Fig. 1b. Control, n = 10; ESP1, n = 8; ESP1 + ESP22, n = 9. c Quantification of the number of mounts made by males, lordosis ratio, and rejection ratio, with each gray dot representing data for an individual animal. Error bars, S.E.M. **p < 0.01 and *p < 0.05 by Steel-Dwass test. d Schematic setup and timeline for the reproduction assay. ESP22 or ESP1 was continuously supplied in the drinking water. Female mice at the beginning of estrus were mated for 10 days, with parturition events monitored daily. e A cumulative plot showing the percentage of females with pups (y-axis) with respect to the days since mating (x-axis). f The proportion of females in each parturition day category since mating. *p < 0.05 by relative risk analysis compared with control (female mice in each group, n = 21)
