Fig. 5
Gene and KEGG pathways enriched with eeSNVs in the five scRNA-seq datasets. a Bipartite graph using significant KEGG pathways and genes enriched with eeSNVs as nodes. An edge exists between a significant pathway and a gene if this gene is part of the pathway. Genes of each data set is represented with a distinct color. The size of the nodes reflects the gene and the pathway scores. The gene scores are computed by SSrGE and the pathway scores are the sum of the gene scores linked for each pathway. b KEGG pathways enriched within the top 100 genes based on eeSNV contributions in the five datasets. Pathways are sorted by the sum of the −log10 (p-value) of each dataset, in the descending order
