Fig. 6 | Nature Communications

Fig. 6

From: Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap

Fig. 6

Atg7-KO gene signature is enriched in transcriptome profiles of human NAFLD liver tissues and HCCs. a Gene set enrichment analysis of transcriptome profiles of NAFLD liver tissues (n = 74, advanced (F3, F4) and mild (F0, F1)) with Atg7-KO gene signature and Yap activation signatures. b Gene set enrichment analysis of transcriptome profiles of human HCC tissues with Atg7-KO gene signature and Yap activation signatures. c Immunofluorescence analysis of human HCC tissue for YAP and P62/SQSTM1. Large insets present magnification of small insets. Scale bar indicates 100 µm

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