Fig. 4 | Nature Communications

Fig. 4

From: A semi-supervised approach for predicting cell-type specific functional consequences of non-coding variation using MPRAs

Fig. 4

Gene expression patterns for genes with cell-line-specific functional variants in promoters. Each bar presents the median expression in one cell line for genes with cell-line-specific functional variants in promoters relative to the median expression for these genes in the other two cell lines combined. The p-values are calculated by testing whether the expression in the matched cell line is greater than the other two cell lines combined, using the Wilcoxon rank sum test. The GenoNet threshold to define functional/non-functional variants in promoter region of a gene is 0.9/0.5

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