Table 2 Table of kinetic constant values for the USP25 oligomers
From: A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25
USP25 constructs | Vmax (nM s−1) | KM (µM) | Kcat (s−1) | Kcat/KM (105 M−1 s−1) |
|---|---|---|---|---|
USP25NCD tetramer | 2.11 ± 0.16 | 27.72 ± 4.68 | 0.42 ± 0.03 | 0.153 |
USP25NCD ∆IL | 5.66 ± 0.31 | 38.68 ± 4.20 | 1.13 ± 0.06 | 0.293 |
USP25NCD ∆LCC-IL | 0.55 ± 0.03 | 20.17 ± 2.42 | 0.11 ± 0.01 | 0.055 |
