Fig. 2 | Nature Communications

Fig. 2

From: GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis

Fig. 2

Effects of gender, age, and systemic sclerosis on autoantibody correlations. We analyzed the relationships among the different autoantibodies (aab) in sera from healthy donors (HD) and the effects of gender and age, as shown by circular networks based on Spearman’s rank correlation coefficients for aab. Circle plots show the correlation matrix of aab comparing each condition: a all HD evaluated, b patients with systemic sclerosis (SSc; Supplementary Table 1, cohort 1; Supplementary Table 2, aab dataset 1); subgroups of HD (cohort 1) analyzed according to c, d gender and e, f age (< and ≥65 years)

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