Fig. 5
From: aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability
aPKCλ is involved in vascular tumor malignancy. a Staining of c-Myc, b FoxO1, c aPKC, or d pSer218-FoxO1 (all red channel) and VE-cadherin (green) with Hoechst 33342 (blue) in malignant angiosarcoma (upper panels) and benign pyogenic granuloma (lower panels) tissue samples. Higher magnification fields are indicated with dashed boxes. Box 1 indicates VE-Cadherin positive regions and box 2 indicates VE-cadherin negative regions. Scale bar in the left panels represents 50 μm. Scale bar in the higher magnification field represents 10 µm
