Fig. 5
From: Functional genomic analysis identifies miRNA repertoire regulating C. elegans oocyte development
Oocyte-expressed miRNAs regulate fertility. a Bar graphs represent number of embryos laid per animal over the course of its life time. Wild-type animals generate ~250 embryos at 20 °C, each of the miRNA mutants generated 100–150 embryos. Each experiment was repeated three times, and each time five animals were counted for their number of progenies. Statistical significance was calculated with one-way ANOVA with the Bonferroni’s correction. ****P < 0.0001, **P < 0.01. ± SD. b Bar graphs represent the percent of embryos that hatch and develop into larvae. Embryos from mir-35–41 mutants display reduced embryonic survival. Each experiment was repeated three times, and each time five animals were counted for any embryonic lethality of their progeny. All the embryos deposited on the plate by each mutant were assayed for development to larval stages. Lack of development to larval stage was scored as embryonic lethality. Statistical significance was calculated by one-way ANOVA with the Bonferroni’s correction. ****P < 0.0001. ± SD
