Fig. 4

Co-evolution-predicted distance constraints for TssF and for TssG. a, b Ribbon diagrams of TssF a and TssG b showing coevolving pairs of residues with lines colored according to the distance between coevolving residues: green, Cα < 6 Å; yellow, Cα < 10 Å; red, Cα > 10 Å. The insets show contact maps from the models (light gray dots) and those predicted from co-evolution data (blue dots). The gray dots are residue contacts from 5 A (dark gray) to 10 A (light gray). The blue dots are predicted contacts, with the darker and larger dots indicating higher confidence