Fig. 2
From: Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
Survival of IPs with relatives belonging to the 1st until 60th percentile survivors of their birth cohort. This figure depicts the hazard ratio (HR) for IPs (left column, panels a–d) with 1 and 2 parents (panels a and c) or 1 and 2+ siblings (panels b and d) belonging to the top x percentile (x = 1,2,3, …, 60) survivors of their birth cohort. The percentile groups (x-axis) are mutually inclusive, meaning that a first-degree family member who belonged to the top 1% also belonged to the top 5%, etc. The figure also depicts the cumulative hazard (CH) for index persons (IPs, right column, panels e–h) with 1 and 2 parents (panels e and g) or 1 and 2+ siblings (panels f and h) who belong to the top 10%. Green (dotted) lines present the reference group of 0 top x percentile parents or siblings, yellow lines represent 1 top x percentile parents or siblings, blue lines represent 2 or 2+ top x percentile parents or siblings. Left column: x-axes represent the top x birth cohort-based survival percentile, the y-axes represent the hazard ratio (HR) of dying for IPs having 1 and 2 or 2+ top x percentile parents or siblings compared to having 0 top x percentile parents or siblings. Right column: x-axes represent IP years of survival, y-axes represent the IPs’ cumulative hazard of dying while having 1 and 2 or 2+ top 10th percentile parents or siblings compared to having 0 top 10th percentile parents or siblings. All estimates are adjusted for religion (UPDB only), sibship size, birth cohort, sex, socio-economic status, mother’s age at birth, birth order, birth intervals, twin birth, and number of top 10% parents or number of top 10% siblings for the sibling and parent analyses, respectively. Error bars represent confidence intervals
