Fig. 3

Hazard ratio for IPs grouped by their relatives’ survival in mutually exclusive groups. Parent and sibling groups: group 1 = IPs of whom the longest lived parent/sibling belonged to the [≥0th & ≤1th percentile] of their birth cohort, group 2 = IPs of whom the longest lived parent/sibling belonged to the [≥1th & ≤5th percentile], group 3 = IPs of whom the longest lived parent/sibling belonged to the [≥5th & ≤10th percentile], group 4 = IPs of whom the longest lived parent/sibling belonged to the [≥10th & ≤15th percentile], group 5 = IPs of whom the longest lived parent/sibling belonged to the [≥15th & ≤20th percentile], group 6 = IPs of whom the longest lived parent/sibling belonged to the [≥20th & ≤100th percentile]. The left column (panels a and b) shows the HRs of IP groups 1–5 compared to group 6 and depicts a parental grouping. The right column (panels c and d) shows the HRs of IP groups 1–5 compared to group 6 and depicts a sibling grouping. Groups were colored by the extremity of the HR. The darker the blue the stronger the survival benefit, the darker the red, the weaker the survival benefit and the effect was not significant with the red colors. The green lines represent the reference category, which is group 6. N_{green line} at the top-right = 4759, N_{green line} at the top-left = 4227, N_{green line} at the bottom-right = 7477, N_{green line} at the bottom-left = 5907. All estimates are adjusted for religion (UPDB only), sibship size, birth cohort, sex, socio-economic status, mother’s age at birth, birth order, birth intervals, twin birth, and number of top 10% parents or number of top 10% siblings for the sibling and parent analyses, respectively. Error bars represent confidence intervals