Fig. 8 | Nature Communications

Fig. 8

From: Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis

Fig. 8

Effects of IEC Napepld deletion on the gut microbiota. a Principal coordinates analysis (PcoA) based on the unweighted UniFrac analysis on operational taxonomic units (OTUs). Each symbol representing a single sample is colored according to its group. b Composition of abundant bacterial phyla identified in the gut microbiota. c Relative abundances (percentage of 16S rRNA gene sequences) of the different bacterial families in each sample. d OTUs significantly affected in HFD-fed Napepld∆IEC mice versus WT mice. A representative 16S rRNA gene from each of the 75 differentially expressed OTUs was aligned and used to infer the phylogenetic tree shown in this figure (n = 9–10). Purple: WT HFD mice and pink: Napepld∆IEC HFD mice. Ten., Tenericutes; Prot., Proteobacteria; Def., Deferribacteres; Bact., Bacteroidaceae; Rik., Rikenellaceae; Pep., Peptococcaceae; Lac., Lachnospiraceae; Des., Desulfovibrionaceae; Def., Deferribacteraceae; Un., Unknown

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