Fig. 6 | Nature Communications

Fig. 6

From: Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy

Fig. 6

In vivo EDT on HepG2 cell derived mouse model. a Photographs on the 0, 2nd, 6th, 14th day of tumour-bearing mice after various treatments by intravenous injection. Dose: PBS (100 μL), NGs (100 μL, 5 mg mL−1), SCNGs (100 μL, 5 mg mL−1). The relative tumour volume (b) and body weight (c) change curves of each group of mice in 14 days after various treatments. Date are the means ± s.d. (n = 3). p values were analyzed by Student’s two-sided t-test (*P < 0.05). d Histopathology analysis (H&E staining, TUNEL and KI-67 assay) of the tumour tissue after 14 days of different treatments. Scale bar, 200 μm. e H&E staining of the major organs of each group of mice after 14 days of different treatments. Scale bar, 200 μm. Source data are provided as a Source Data file

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